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03.02
2026

VP Platform Chemistry

About the company

Orbis Medicines is a pioneering biotech company powered by its automated nGen chemistry platform and a data-driven approach. The company develops oral alternatives to injectable biologics, designing macrocycles with oral bioavailability through the combination of AI technologies, automated synthesis, and high-throughput screening.

About the role

Orbis is seeking a VP Platform Chemistry to lead and continuously innovate its automated macrocycle synthesis platform. This role involves defining the strategic direction of the chemistry engine, driving platform innovation, and ensuring world-class execution across discovery programs while being a key member of the R&D leadership team.

Key requirements

  • PhD in Chemistry, Pharmaceutical Sciences, or related field

  • 12+ years of industry experience in macrocycle or complex synthetic chemistry

  • Proven experience building automated or high-throughput synthesis platforms

  • Strong understanding of macrocycle chemistry and DMTA-driven discovery cycles


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