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16.10.2019 ICHNOS SCIENCES LAUNCHES AS NEW, INDEPENDENT, LEADING-EDGE BIOTECH DEDICATED TO OUTPACING DISEASE

  • Ichnos Sciences is a new biotechnology company which is a spin-off of Glenmark Holding SA created to focus on innovation
  • Pipeline includes five novel, first-in-class clinical-stage assets in oncology, autoimmune disease and pain
  • Company assets include: BEAT® (Bispecific Engagement by Antibodies based on the T cell receptor), a proprietary platform; a development site, two research centers; a GMP biologics manufacturing facility and ~350 employees worldwide

 

Ichnos (‘īk-nōz) Sciences officially opened its doors to the world today as an independent, fully integrated, global biotech company. A spin-off of Glenmark Holding SA, a global pharmaceutical company with a track-record of improving patients’ lives by providing affordable medicines, the newly formed company was first approved in principle by the Glenmark Board of Directors in February 2019 and now operates with its own board of directors and executive team. Former Gilead executive, Alessandro Riva, MD, is CEO of Ichnos Sciences.
“Ichnos Sciences takes its name from an ancient Greek word that means ’footprint,’ and is dedicated to transforming how people think about and treat cancer, autoimmune disease and pain, and to leaving an imprint on the lives of those affected by disease,” Dr. Riva said. “The Company takes a holistic, disease-centric approach to research, has been structured to work faster, smarter and more collaboratively to accelerate development and quickly bring new treatments to patients.”

Ichnos Sciences, headquartered in Paramus, N.J., launches with a firm global footprint that includes two research centers (Biologics in Switzerland and small molecules in Mahape, Navi Mumbai, India), a development site (Paramus, N.J.) and a GMP biologics manufacturing facility (Switzerland). Approximately 350 employees work at the Company and are dedicated to accelerating candidates in the pipeline toward commercialization.

Ichnos Sciences’ current pipeline includes three new biological entities (NBE) and two new chemical entities (NCE) in various stages of development across oncology, autoimmune disease and pain. The immuno-oncology biologics pipeline is developed through the Company’s proprietary BEAT® (Bispecific Engagement by Antibodies based on the T cell receptor) platform.

GBR 1342, the Company’s CD38xCD3 bispecific antibody (bsAb) under development for relapsed & refractory multiple myeloma, was recently granted orphan drug designation by the U.S. Food and Drug Administration.
Overall, Ichnos Sciences’ goals are to:

  • Rapidly advance its pipeline of clinical-stage assets. Key readouts for four of its five pipeline candidates are expected starting in 2020
  • Invest in NBE and NCE discovery in oncology and autoimmune disease to develop next generation of biologics and small molecules

 

“We are building on the contributions of those who came before while paving a new path forward,” Dr. Riva said. “We will imprint our mark forever by transforming the way we treat diseases. We dare to imagine a world where cure is possible.”
Ichnos Sciences is in the process of obtaining all the necessary statutory, legal, corporate and regulatory approvals for completion of the spin-off, which is expected to occur in the first quarter of calendar year 2020.

 

About Ichnos Sciences
A fully integrated, global biotech with the spirit of a start-up, Ichnos Sciences is shifting the way the world thinks about innovation in medicine through its research and development of transformative, disease-centric treatments in oncology, autoimmune disease and pain. The Company, with headquarters in Paramus, N.J., is rapidly advancing a clinical-stage pipeline of novel, first-in-class candidates designed to address complex diseases and treat patients holistically. With a patented BEAT® technology platform along with pioneering teams in Switzerland and India, Ichnos Sciences has a mission to provide breakthrough, curative therapies that will hopefully extend and improve lives, writing a new chapter in healthcare.

For more information, visit IchnosSciences.com.

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